Karen T Liby Selected Research

Dimethyl Fumarate

7/2015

Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Karen T Liby Research Topics

Disease

47	Neoplasms (Cancer) 03/2024 - 09/2004
16	Inflammation (Inflammations) 12/2023 - 02/2006
14	Carcinogenesis 01/2023 - 02/2006
14	Breast Neoplasms (Breast Cancer) 01/2022 - 09/2004
8	Lung Neoplasms (Lung Cancer) 03/2024 - 01/2014
6	Pancreatic Neoplasms (Pancreatic Cancer) 12/2020 - 03/2010
5	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 12/2023 - 01/2019
4	Neoplasm Metastasis (Metastasis) 10/2018 - 03/2011
4	Body Weight (Weight, Body) 11/2009 - 02/2006
3	Obesity 10/2023 - 10/2009
3	Triple Negative Breast Neoplasms 10/2023 - 01/2014
3	Melanoma (Melanoma, Malignant) 08/2023 - 03/2011
3	Carcinoma (Carcinomatosis) 10/2015 - 03/2010
3	Chronic Disease (Chronic Diseases) 01/2014 - 01/2012
2	Pancreatitis 12/2020 - 12/2018
2	Parkinson Disease (Parkinson's Disease) 01/2013 - 06/2009
2	Neuroinflammatory Diseases 07/2011 - 01/2011
1	Airway Obstruction (Choking) 01/2023
1	Toxic Optic Neuropathy 01/2023
1	Hyperplasia 01/2021
1	Hypertriglyceridemia 12/2020
1	Hepatomegaly 01/2019
1	Alopecia (Baldness) 01/2019
1	Cerebral Malaria 11/2017

Drug/Important Bio-Agent (IBA)

29	TriterpenesIBA 08/2023 - 02/2006
17	bardoxoloneIBA 11/2017 - 09/2004
15	1- (2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oyl) imidazoleIBA 12/2016 - 09/2004
13	bardoxolone methylIBA 08/2023 - 09/2004
8	Bexarotene (LGD1069)FDA Link 12/2023 - 01/2019
8	oleananeIBA 11/2017 - 05/2007
7	AcidsIBA 08/2023 - 09/2004
6	Retinoid X Receptors (Retinoid X Receptor)IBA 12/2023 - 01/2019
6	Proteins (Proteins, Gene)FDA Link 01/2018 - 11/2009
5	CytokinesIBA 03/2024 - 01/2011
5	EnzymesIBA 12/2018 - 01/2007
5	imidazoleIBA 03/2011 - 02/2006
4	Transcription Factors (Transcription Factor)IBA 03/2024 - 11/2009
4	EstersIBA 08/2023 - 03/2010
4	CarcinogensIBA 03/2023 - 10/2015
4	vinyl carbamateIBA 10/2021 - 10/2015
4	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2021 - 07/2014
4	LG 100268IBA 01/2019 - 11/2010
3	Immune Checkpoint InhibitorsIBA 03/2024 - 01/2019
3	LigandsIBA 12/2023 - 01/2019
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 12/2023 - 01/2021
3	talazoparibIBA 01/2021 - 01/2017
2	Estrogens (Estrogen)FDA Link 10/2023 - 01/2021
2	RNA (Ribonucleic Acid)IBA 02/2023 - 01/2007
2	Interleukin-6 (Interleukin 6)IBA 01/2023 - 01/2017
2	AntibodiesIBA 10/2021 - 01/2019
2	Estrogen ReceptorsIBA 01/2020 - 01/2013
2	LG 268IBA 01/2019 - 11/2010
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2018 - 01/2017
2	Cyclin D1IBA 10/2018 - 01/2012
2	Phosphotransferases (Kinase)IBA 10/2018 - 09/2013
2	2- cyano- 3,12- dioxooleana- 1,9(11)- dien- 28- oic acid ethyl amideIBA 11/2017 - 11/2010
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2016 - 01/2014
2	Histone Deacetylase InhibitorsIBA 01/2016 - 01/2013
2	Vorinostat FDA Link 01/2016 - 01/2013
2	Carboplatin (JM8)FDA LinkGeneric 01/2016 - 01/2014
2	Interleukin-17 (Interleukin 17)IBA 12/2014 - 01/2011
2	Messenger RNA (mRNA)IBA 01/2013 - 01/2011
2	NF-E2-Related Factor 2IBA 07/2011 - 06/2009
2	Neuroprotective AgentsIBA 07/2011 - 06/2009
2	(2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oic acid) trifluoroethylamideIBA 07/2011 - 01/2011
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2011 - 08/2006
2	AntioxidantsIBA 01/2011 - 11/2009
2	Oleanolic AcidIBA 01/2011 - 02/2006
2	Gemcitabine FDA Link 11/2010 - 03/2010
1	Kelch-Like ECH-Associated Protein 1IBA 03/2024
1	KynurenineIBA 10/2023
1	Tryptophan (L-Tryptophan)FDA Link 10/2023
1	Progesterone Receptors (Progesterone Receptor)IBA 10/2023
1	Hormones (Hormone)IBA 10/2023
1	VemurafenibIBA 08/2023
1	PLX 4720IBA 08/2023
1	Small Cytoplasmic RNAIBA 08/2023
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2023
1	PesticidesIBA 01/2023
1	chloropicrinIBA 01/2023
1	AgarIBA 01/2021
1	INCB057643IBA 12/2020
1	Liposomes (Liposome)IBA 01/2019
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	CholesterolIBA 01/2019
1	AntigensIBA 12/2018
1	CeruletideIBA 12/2018
1	OligopeptidesIBA 12/2018
1	Protein Isoforms (Isoforms)IBA 10/2018
1	OximesIBA 10/2018
1	Immunomodulating AgentsIBA 11/2017
1	Antimalarials (Antimalarial Agents)IBA 11/2017
1	ArtesunateIBA 11/2017

Therapy/Procedure

10	Therapeutics 03/2024 - 07/2015
9	Chemoprevention 03/2021 - 10/2005
4	Oral Administration 09/2013 - 11/2009
3	Immunotherapy 01/2022 - 03/2010
2	Immunomodulation 01/2021 - 01/2019
1	Drug Therapy (Chemotherapy) 01/2021
1	Radical Mastectomy 01/2021